Browsing by Author "Ezquer, Marcelo"

Now showing items 1-6 of 6

    • A dual treatment blocks alcohol binge-drinking relapse: microbiota as a new player 
      Ezquer, Fernando; Quintanilla González, María Elena; Morales Retamales, Eugenia; Santapaul, Daniela; Munita, José Manuel; Moya Flores, Francisco; Ezquer, Marcelo; Herrera Marschitz, Mario; Israel Jacard, Yedy (Elsevier, 2022)
      Rationale: Gut microbiota communicates information to the brain. Some animals are born with a gut microbiota that predisposes to high alcohol consumption, and transplantation of fecal material from alcoholics to mice ...
    • A novel morphine drinking model of opioid dependence in rats 
      Berrios Cárcamo, Pablo; Quezada, Mauricio; Santapau, Daniela; Morales Retamales, Eugenia; Olivares, Belén; Ponce, Carolina; Ávila, Alba; Gregorio, Cristian de; Ezquer, Marcelo; Quintanilla González, María Elena; Herrera-Marschitz Muller, Mario; Israel Jacard, Yedy; Ezquer, Fernando (MDPI, 2022)
      An animal model of voluntary oral morphine consumption would allow for a pre-clinical evaluation of new treatments aimed at reducing opioid intake in humans. However, the main limitation of oral morphine consumption in ...
    • Administration of N-acetylcysteine plus acetylsalicylic acid markedly inhibits nicotine reinstatement ... 
      Quintanilla González, María Elena; Morales Retamales, Paola; Ezquer, Fernando; Ezquer, Marcelo; Herrera-Marschitz Muller, Mario; Israel, Yedy (Frontiers Media, 2021)
      Background Nicotine is the major addictive component of cigarette smoke and the prime culprit of the failure to quit smoking. Common elements perpetuating the use of addictive drugs are (i) cues associated with the ...
    • Intravenous administration of anti-inflammatory mesenchymal stem cell spheroids reduces chronic alcohol ... 
      Ezquer, Fernando; Morales Retamales, Paola; Quintanilla González, María Elena; Santapau, Daniela; Lespay Rebolledo, Carolyne; Ezquer, Marcelo; Herrera-Marschitz Muller, Mario; Israel Jacard, Yedy (Nature, 2018)
      Chronic alcohol intake leads to neuroinflammation and astrocyte dysfunction, proposed to perpetuate alcohol consumption and to promote conditioned relapse-like binge drinking. In the present study, human mesenchymal stem ...
    • Intravitreal administration of multipotent mesenchymal stromal cells triggers a cytoprotective microenvironment ... 
      Ezquer, Marcelo; Urzúa Salinas, Cristhian; Montecino, Scarleth; Conget, Paulette; Ezquer, Fernando (BioMed Central, 2016)
      Background: Diabetic retinopathy is a common complication of diabetes and the leading cause of irreversible vision loss in the Western world. The reduction in color/contrast sensitivity due to the loss of neural cells in ...
    • Spatial maps and oscillations in the healthy hippocampus of octodon degus, a natural model of sporadic ... 
      Mugnaini, Matias; Polania Caviedes, Diana Marcela; Díaz, Yannina; Ezquer, Marcelo; Ezquer, Fernando; Deacon, Robert M. J.; Cogram, Patricia; Kropf, Emilio (Nature, 2022)
      The Octodon degus is a South American rodent that is receiving increased attention as a potential model of aging and sporadic late-onset Alzheimer's disease (AD). Impairments in spatial memory tasks in Octodon degus have ...